alleryStart learning →What is the consensus sequence of the -10 region of a prokaryotic promoter?
ATATAAT
BTTGACA
CGGCCAATCT
DATTTGCAT
Answer & Solution
Correct answer: A. TATAAT
1. Prokaryotic promoters carry two conserved elements, one at -10 and one at -35 relative to the initiation site.
2. The -10 consensus sequence is TATAAT.
3. Its A and T rich composition lowers duplex stability and helps the template unwind.
4. TTGACA sits at -35, so it answers the neighbouring question rather than this one.
5. GGCCAATCT is the eukaryotic CAAT box, so it belongs to a different kind of promoter.
6. ATTTGCAT is the eukaryotic octamer box and is nonessential even there.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.2 Prokaryotic Transcription_
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