How many commonly occurring amino acids make up the protein alphabet?
ASixteen amino acids
BTwenty amino acids
CSixty-four amino acids
DSixty-one amino acids
Answer & Solution
Correct answer: B. Twenty amino acids
1. Protein sequences are built from 20 commonly occurring amino acids, so the protein alphabet has 20 letters.
2. Sixteen is the number of possible two-nucleotide combinations, not the number of amino acids.
3. Sixty-four counts the possible nucleotide triplets, and 61 of those triplets specify amino acids.
4. Only the count of 20 answers the question asked.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.1 The Genetic Code_
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