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The presence of an "origin of replication" is important because it
A{'text': 'Codes for a specific antibiotic resistance protein product', 'label': 'A'}
B{'text': 'Suppresses transcription of nearby cloned target genes', 'label': 'B'}
C{'text': 'Adds sticky single-strand overhangs to a DNA fragment cut', 'label': 'C'}
D{'text': 'Initiates DNA replication so that the sequence can be copied', 'label': 'D'}
Answer & Solution
Correct answer: D. {'text': 'Initiates DNA replication so that the sequence can be copied', 'label': 'D'}
1. Any alien DNA in a host needs a way to replicate along with the host.
2. The origin of replication (ori) is the DNA sequence at which replication initiates.
3. Only DNA linked to an ori (or integrated into a host chromosome) can be reliably copied.
4. Vectors like plasmids therefore carry an ori so the inserted gene is propagated.
_Source: NCERT Class 12 Biology, Ch 9 "Biotechnology: Principles and Processes", §9.1_
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