Home › Maharashtra HSC Class 12 (Science) › biology › Molecular Basis of Inheritance › Semiconservative DNA replication was experimenta…
Semiconservative DNA replication was experimentally demonstrated by
AHershey and Chase
BMeselson and Stahl
CAvery, MacLeod and McCarty
DGriffith
Answer & Solution
Correct answer: B. Meselson and Stahl
1. Meselson and Stahl labelled DNA with heavy ¹⁵N then shifted bacteria to light ¹⁴N medium.
2. Density-gradient centrifugation of progeny DNA showed intermediate density in generation I and a mix of hybrid and light in generation II.
3. This pattern matches the semiconservative replication model.
_Source: Maharashtra Balbharati Std XII Biology, Ch 4 "Molecular Basis of Inheritance" §4.5_
Related questions
In eukaryotes, primary mRNA transcript becomes mature mRNA afterThe 'one gene - one polypeptide' concept was proposed byIn prokaryotes, the small ribosomal subunit recognises the mRNA initiation site via theIn humans, the percentage of A in a DNA sample is 30 %. By Chargaff's rule, the percentageTranscription differs from replication in that itThe genetic code is described as degenerate becauseOkazaki fragments are formed on theDuring DNA replication, the enzyme that unwinds the double helix is