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Type-1 diabetes mellitus (IDDM) is caused by:
ATarget cells failing to respond to insulin
BExcess deposition of cholesterol in vessels
CAccumulation of excess fat in the body
DDestruction of the beta-cells of the pancreas
Answer & Solution
Correct answer: D. Destruction of the beta-cells of the pancreas
1. Type-1 (IDDM) shows abnormally high blood glucose from inadequate insulin secretion.
2. It results from destruction of the insulin-producing beta-cells of the pancreas.
3. Option A describes Type-2 (NIDDM) where insulin action is impaired, so it is the key trap.
4. Cholesterol deposition and fat accumulation relate to heart disease and obesity, not Type-1 diabetes.
5. Hence the answer is D.
_Source: Samacheer Kalvi (TN SCERT) Class 10 Science, Unit "Health and Diseases", p.312_
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