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**Okazaki fragments** on the lagging strand are joined together by the enzyme:
ADNA polymerase I
BDNA polymerase III
CDNA ligase
DHelicase
Answer & Solution
Correct answer: C. DNA ligase
DNA ligase seals the nicks (phosphodiester bonds) between adjacent Okazaki fragments after the RNA primers are removed and replaced with DNA. Polymerases extend strands; helicase unwinds the parent duplex; ligase joins.
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