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The **histones** that wrap DNA into nucleosomes are positively charged because they are rich in which amino acids?
AGlutamate and aspartate (acidic)
BLysine and arginine (basic)
CCysteine and methionine (sulphur)
DPhenylalanine and tyrosine (aromatic)
Answer & Solution
Correct answer: B. Lysine and arginine (basic)
Lysine and arginine carry positive side-chain charges at cellular pH. The positively charged histones bind the negatively charged DNA backbone (phosphate groups) — electrostatic attraction enables wrapping.
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