Anaplerotic reactions in cellular metabolism
AUse ATP to drive flow against the gradient
BReduce NAD+ to NADH for glycolysis only
CConvert glucose into starch storage forms
DReplenish TCA intermediates lost to biosynthesis
Answer & Solution
Correct answer: D. Replenish TCA intermediates lost to biosynthesis
If TCA intermediates are withdrawn for biosynthesis (e.g., OAA for aspartate or gluconeogenesis), the cycle would stall. Anaplerotic reactions (e.g., pyruvate carboxylase generates OAA from pyruvate + CO2) replenish them.
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