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Per turn of the Krebs cycle, acetyl-CoA combines with which molecule first?
Aoxaloacetate, to form citrate (6-carbon)
Bpyruvate, to give lactate intermediate
Cglucose, to give fructose phosphate
DATP, to give ADP and Pi separately
Answer & Solution
Correct answer: A. oxaloacetate, to form citrate (6-carbon)
Each turn begins when acetyl-CoA (2C) joins oxaloacetate (4C) to form citrate (6C). Citrate is the namesake of the cycle. Oxaloacetate is regenerated at the cycle's end so the loop can run again.
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