Pyruvate dehydrogenase converts pyruvate to
AAcetyl CoA with CO2 and NADH released
BLactic acid with NAD+ regeneration
CEthanol with CO2 and NAD+ regenerated
DCitric acid by condensation with OAA
Answer & Solution
Correct answer: A. Acetyl CoA with CO2 and NADH released
Oxidative decarboxylation of pyruvate in the mitochondrial matrix by pyruvate dehydrogenase produces acetyl CoA + CO2 + NADH. The reaction needs CoA, NAD+, and Mg2+.
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