In the Watson-Crick model, the two polynucleotide strands of DNA are:
- Perpendicular
- Anti-parallel (one 5′→3′, the other 3′→5′)
- Parallel (both 5′→3′ in the same direction)
- Random in orientation
Show answer and solution
Correct answer: B. Anti-parallel (one 5′→3′, the other 3′→5′)
**Anti-parallel** strands: one runs 5′→3′, the other 3′→5′.
This is essential for base pairing and for the directionality of replication.