The osmolarity of the medullary interstitium ranges approximately from
- 50 to 150 mOsm/L in the medulla
- 300 to 1200 mOsm/L in the medulla
- Always 300 mOsm/L like blood plasma
- Always 1200 mOsm/L like inner medulla
Show answer and solution
Correct answer: B. 300 to 1200 mOsm/L in the medulla
The corticomedullary osmotic gradient runs from ~300 mOsm/L in the cortex to ~1200 mOsm/L in the inner medulla.
NaCl and urea recycling produce the gradient.
Human kidneys can concentrate urine to about 4x plasma.