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Which enzyme is the target of the drug methotrexate?

ACytochrome c oxidase
BSuccinic dehydrogenase
CDihydrofolate reductase
DCarbonic anhydrase
Answer & Solution
Correct answer: C. Dihydrofolate reductase
Methotrexate resembles dihydrofolate and competes for the active site of dihydrofolate reductase.
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