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How does a non-competitive inhibitor change enzyme kinetics?

ARaises Km, Vmax unchanged
BLowers Vmax, Km unchanged
CRaises both Km and Vmax
DLowers Km, Vmax unchanged
Answer & Solution
Correct answer: B. Lowers Vmax, Km unchanged
It binds away from the substrate site, so substrate affinity and Km stay the same while Vmax falls.
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