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Thick filaments in skeletal muscle are made of:
ACollagen
BMyosin
CActin
DTropomyosin
Answer & Solution
Correct answer: B. Myosin
Thick filaments: myosin II. Each thick filament: ~300 myosin molecules bundled. Each myosin has 2 heavy chains (with 2 heads and a coiled-coil tail) + 4 light chains. Heads form cross-bridges with actin, hydrolyze ATP, generate force. Thin filaments: actin (helical filament of G-actin monomers) + tropomyosin + troponin.
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