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Hypothalamus secretes releasing and inhibiting hormones that act on:

APosterior pituitary
BThyroid directly
CAdrenal cortex
DAnterior pituitary via hypothalamo-hypophyseal portal system
Answer & Solution
Correct answer: D. Anterior pituitary via hypothalamo-hypophyseal portal system
Hypothalamus produces releasing hormones (TRH, CRH, GnRH, GHRH) and inhibiting hormones (somatostatin, dopamine). These travel via portal blood vessels to anterior pituitary, controlling its secretions. Posterior pituitary stores hypothalamic ADH and oxytocin (different mechanism).
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