Vitamin B12 contains which metal at its center?
ACobalt (only Co-containing biomolecule; in corrin ring)
BZinc
CMagnesium
DIron
Answer & Solution
Correct answer: A. Cobalt (only Co-containing biomolecule; in corrin ring)
**B12 (cobalamin):** central Co atom in corrin ring (similar to but smaller than porphyrin).
Only Co-containing biomolecule known.
Hemoglobin has Fe in porphyrin; chlorophyll has Mg.
B12 essential for nucleic acid synthesis, neurological function
deficiency causes pernicious anemia.
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