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The enzyme that lays down a short RNA piece to start replication is:

APeptidase
BPermease
CPrimase
DProtease
Answer & Solution
Correct answer: C. Primase
1. DNA polymerase cannot start from nothing. 2. A short RNA primer is needed first. 3. Primase makes it. _Source: OpenStax Biology 2e, Chapter 14, DNA Structure and Function._
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