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In the DNA double helix, guanine always pairs with:

AThymine
BAdenine
CUracil
DCytosine
Answer & Solution
Correct answer: D. Cytosine
1. Purines pair with pyrimidines. 2. Chargaff's rules fix the partners. 3. So guanine pairs with cytosine. _Source: OpenStax Biology 2e, Chapter 14, DNA Structure and Function._
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