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The Law of Octaves broke down for heavier elements and was fully upset by the discovery of:

ANatural isotopes
BNoble gases
CNuclear fission
DNeutron beams
Answer & Solution
Correct answer: B. Noble gases
1. A whole new family of elements was found later. 2. Adding them shifted every eighth position. 3. Those were the noble gases. _Source: syllabus Science Class X, Chapter 5, Periodic Classification of Elements._
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