'Microsatellite DNA' is used in the case of which one of the following?
AStudying the evolutionary relationships among various species of fauna
BStimulating 'stem cells' to transform into diverse functional tissues
CPromoting clonal propagation of horticultural plants
DAssessing the efficacy of drugs by conducting series of drug trials in a population
Answer & Solution
Correct answer: A. Studying the evolutionary relationships among various species of fauna
Answer: A. Microsatellite DNA is used for studying evolutionary relationships among species.
Microsatellites (also called Simple Sequence Repeats or SSRs) are tandemly repeated DNA sequences of 1-6 base pairs (e.g., CACACA, GTGTGT) distributed throughout the genome. They have high mutation rates and are highly polymorphic, making them excellent genetic markers.
Applications include:
- Population genetics: studying evolutionary relationships, gene flow, genetic diversity
- Phylogeography: mapping species distribution and history
- Wildlife forensics: identifying poached animal species and individuals
- Paternity testing in animals and humans
- Conservation genetics: assessing endangered species
Distractors:
(B) Stem cell differentiation uses transcription factors and growth factors, not microsatellite DNA.
(C) Clonal propagation uses tissue culture, micropropagation; microsatellites only confirm clonal identity.
(D) Drug efficacy uses clinical trial protocols, not microsatellite DNA.
Source: NCERT Class 12 Biology Ch 6 (Molecular Basis of Inheritance) / standard population genetics texts.
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