At which point in Selye's model does the body's ability to resist become depleted, so that illness, disease or even death may follow?

1. The third stage of the general adaptation syndrome is the stage of exhaustion. 2. It arrives when exposure to a stressor continues over a longer period of time. 3. At that point the person can no longer adapt to the stressor and the ability to resist becomes depleted. 4. Physical wear takes its toll on tissues and organs, so illness, disease, permanent damage and even death may occur. 5. The first cascade of alerting reactions is the alarm reaction, the opening stage rather than the closing one. 6. Adaptation holding at lower intensity describes the stage of resistance, which precedes exhaustion. 7. Appraising a stressor as a challenge belongs to primary appraisal and sits outside the three-stage model. _Source: OpenStax Psychology (1st ed., CC BY 4.0), Ch 14 "Stress, Lifestyle, and Health", section 14.1 What Is Stress?_