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Hyposecretion of corticosteroids produces which laboratory picture?
AHigh blood glucose and high blood sodium
BHigh blood glucose and low blood sodium
CLow blood glucose and high blood sodium
DLow blood glucose and low blood sodium
Answer & Solution
Correct answer: D. Low blood glucose and low blood sodium
1. Glucocorticoids raise blood glucose and mineralocorticoids retain sodium.
2. Losing both classes therefore drops blood glucose and blood sodium together.
3. That combination is Addison disease, whose vague signs include weakness, abdominal pain, weight loss and salt craving.
4. The opposite disorder is Cushing disease, from hypersecretion of cortisol, which raises blood glucose.
5. Mixed pictures with one value high and one low would need one corticosteroid class to be spared, which hyposecretion does not do.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 17 "The Endocrine System", section 17.6 The Adrenal Glands_
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