Which enzyme model pictures the active site as flexible, changing shape to bind its substrate?
AThe induced fit model
BThe lock and key model
CThe rigid template model
DThe frozen active site model
Answer & Solution
Correct answer: A. The induced fit model
1. Two models describe how an enzyme's active site takes hold of its substrate.
2. The induced fit model treats the enzyme as flexible, reshaping itself to bond the substrate.
3. The lock and key model instead assumes the two shapes are complementary from the start, like a key in a lock.
_Source: OpenStax Chemistry (CC BY 4.0), Ch 12 "Kinetics", section 12.7 Catalysis_
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