Sertoli cells, a type of sustentacular cell in the seminiferous tubules, form which protective structure?
AThe tunica vaginalis
BThe epididymal septum
CThe blood-testis barrier
DThe spermatic fascia
Answer & Solution
Correct answer: C. The blood-testis barrier
1. Sertoli cells surround developing sperm cells at all stages within the seminiferous tubules.
2. Tight junctions link adjacent Sertoli cells together.
3. This creates a barrier that keeps bloodborne substances away from developing germ cells, and prevents germ cell antigens from leaking into the blood.
4. This structure is called the blood-testis barrier.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 27 "The Reproductive System", p.1283 §Sertoli Cells_
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