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Approximately how far does a thin filament move toward the M-line during a single power stroke of the cross-bridge cycle?

A10 nm
B1.2 μm
C2 μm
D100 nm
Answer & Solution
Correct answer: A. 10 nm
1. During the power stroke, the myosin head pivots after releasing inorganic phosphate, pulling the actin filament. 2. This pull moves the thin filament approximately 10 nm toward the M-line in one stroke. 3. Many repeated cycles across a sarcomere are needed to produce the overall shortening seen in contraction. 4. 1.2 μm is the diameter of a myofibril, a far larger scale than a single power stroke. 5. 2 μm is the length of a whole sarcomere, again much larger than the distance one power stroke covers. 6. 100 nm overstates the real power-stroke distance roughly tenfold. _Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 10 "Muscle Tissue", section 10.3, p. 417_
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