What distinguishes a pericentric inversion from a paracentric one?
AA pericentric inversion is always much longer
BA pericentric inversion involves the centromere
CA pericentric inversion occurs during mitosis only
DA pericentric inversion deletes genes as it forms
Answer & Solution
Correct answer: B. A pericentric inversion involves the centromere
1. Inversions are classed by whether the inverted segment spans the centromere.
2. A pericentric inversion includes the centromere.
3. A paracentric inversion occurs outside of the centromere.
4. A pericentric inversion that is asymmetric about the centromere changes the relative lengths of the two arms.
5. That change in arm lengths makes such inversions easy to identify in a karyogram.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 13 "Modern Understandings of Inheritance", section 13.2 Chromosomal Basis of Inherited Disorders_
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