alleryStart learning →What is allosteric inhibition?
ABinding at a site that lowers substrate affinity
BBinding at the active site that mimics a substrate
CBinding that permanently cuts the enzyme in two
DBinding that adds a phosphate to the active site
Answer & Solution
Correct answer: A. Binding at a site that lowers substrate affinity
1. Some inhibitor molecules bind to enzymes at a location where their binding induces a conformational change.
2. That change reduces the affinity of the enzyme for its substrate, and this is called allosteric inhibition.
3. Binding at the active site itself and mimicking the substrate is competitive inhibition instead.
4. No cutting or phosphorylation of the enzyme is involved in allosteric inhibition.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 6 "Metabolism", section 6.5 Enzymes_
Keep practising Metabolism
Browse all Metabolism questions for Ontario Secondary (Grade 9-12), or explore more Biology topics.
Related questions
Pick the metabolism fact, fastMatch the metabolism termsComplete the ATP storyMetabolism: true or false?What is feedback inhibition?Pyruvate dehydrogenase is a multi-enzyme complex. How many cofactors and coenzymes does itVitamin C serves as a coenzyme for enzymes that build which body component?What are the most common sources of coenzymes?