The induced-fit model replaced which earlier picture of enzyme and substrate binding?
AThe lock-and-key model
BThe fluid mosaic model
CThe feedback inhibition model
DThe energy coupling model
Answer & Solution
Correct answer: A. The lock-and-key model
1. For many years scientists thought enzyme and substrate binding took place in a simple lock-and-key fashion.
2. That model asserted the enzyme and substrate fit together perfectly in one instantaneous step.
3. Current research supports a more refined view called induced fit, which expands upon the lock-and-key model.
4. The fluid mosaic model describes membrane structure and has nothing to do with enzyme binding.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 6 "Metabolism", section 6.5 Enzymes_
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