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What is the calculated free energy change for hydrolysis of one mole of ATP under standard conditions?

AMinus 2.1 kcal per mole
BMinus 7.3 kcal per mole
CMinus 18 kcal per mole
DMinus 30.5 kcal per mole
Answer & Solution
Correct answer: B. Minus 7.3 kcal per mole
1. The calculated free energy change for hydrolysis of one mole of ATP into ADP and inorganic phosphate is minus 7.3 kcal per mole. 2. The same quantity expressed in the other unit is minus 30.5 kJ per mole, so 30.5 is the kilojoule figure rather than the kilocalorie figure. 3. The negative sign marks the reaction as exergonic, since energy is released. 4. The value 2.1 kcal per mole is the cost of moving one sodium ion across a membrane, a separate quantity. _Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 6 "Metabolism", section 6.4 ATP: Adenosine Triphosphate_
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