How large a fall in blood volume triggers a rapid surge of ADH release?
AA drop of about 1 percent
BA drop of about 25 percent
CA drop of 5 to 10 percent
DA drop of about 40 percent
Answer & Solution
Correct answer: C. A drop of 5 to 10 percent
1. A fall in blood volume of 5 to 10 percent lowers blood pressure measurably.
2. That triggers a rapid and significant rise in ADH release from the posterior pituitary.
3. At those levels ADH causes immediate vasoconstriction to raise blood pressure.
4. It also activates aquaporin channels in the collecting ducts to recover water and restore vascular volume.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 25 "The Urinary System", section 25.9 Regulation of Fluid Volume and Composition_
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