alleryStart learning →How does B-type natriuretic peptide compare with atrial natriuretic hormone?
ALarger peptide, tenfold stronger at its receptor
BSame size peptide, made in the atrial walls too
CLarger peptide, tenfold weaker at its receptor
DSmaller peptide, made in the kidney medulla
Answer & Solution
Correct answer: C. Larger peptide, tenfold weaker at its receptor
1. Atrial natriuretic hormone has 28 amino acids and comes from the atria.
2. B-type natriuretic peptide has 32 amino acids and comes from the ventricles, so it is the larger of the two.
3. Its affinity for the receptor is tenfold lower, so its effects are weaker than those of the atrial hormone.
4. Its role may be fine tuning of blood pressure regulation rather than bulk correction.
5. Its longer biological half-life makes it a useful diagnostic marker of congestive heart failure.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 25 "The Urinary System", section 25.8 Endocrine Regulation of Kidney Function_
Keep practising The Urinary System
Browse all The Urinary System questions for NEET PG, or explore more Physiology topics.
Related questions
How many times over is the entire blood volume filtered through the kidneys in a day?What proportion of hospitalised patients does acute kidney injury affect?What happens to the bladder in late pregnancy?What is sodium's place in determining plasma osmolarity?What is a diuretic?If no further water reabsorption happened beyond the distal tubule, roughly how much urineWhen the kidney deaminates glutamine, what does the body gain and what does it lose?Which statement describes simple diffusion in the nephron?