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What stimulus causes the heart to release atrial natriuretic hormone?

AOver-stretching of the atrial wall
BA fall in circulating potassium
CA rise in angiotensin II levels
DA drop in extracellular volume
Answer & Solution
Correct answer: A. Over-stretching of the atrial wall
1. Atrial natriuretic hormone is a 28 amino acid peptide produced by the atria of the heart. 2. Its stimulus is over-stretching of the atrial wall. 3. That stretching happens when blood pressure is elevated or the heart is failing. 4. So the hormone appears when volume is too high, which is why its job is to shed sodium and water. _Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 25 "The Urinary System", section 25.8 Endocrine Regulation of Kidney Function_
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