alleryStart learning →How large a pressure differential across the glomerulus is needed for a normal filtration rate?
AAbout 55 mm Hg is required
BAbout 30 mm Hg is required
CAbout 90 mm Hg is required
DAbout 10 mm Hg is required
Answer & Solution
Correct answer: D. About 10 mm Hg is required
1. Net filtration pressure at the glomerulus is small, only about 10 mm Hg.
2. That is all the differential a normal filtration rate requires.
3. Because the working margin is so narrow, small changes in afferent arterial pressure move the filtration rate a great deal.
4. That sensitivity is exactly why the kidney needs myogenic and tubuloglomerular autoregulation to hold the rate steady.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 25 "The Urinary System", section 25.7 Regulation of Renal Blood Flow_
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