alleryStart learning →What share of filtered bicarbonate is reabsorbed in the proximal tubule?
AAbout 80 to 90 percent
BAbout 20 to 30 percent
CAbout 40 to 50 percent
DAbout 5 to 10 percent
Answer & Solution
Correct answer: A. About 80 to 90 percent
1. Bicarbonate is a powerful and fast-acting buffer, so losing it would cost the body dearly.
2. The proximal tubule recovers 80 to 90 percent of the filtered load by symport with sodium.
3. The remainder is handled further along, including antiport with chloride in the collecting ducts.
4. Recovering only a small fraction would leave the plasma unable to buffer the daily acid load.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 25 "The Urinary System", section 25.6 Tubular Reabsorption_
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