alleryStart learning →Why does inulin give a close estimate of the glomerular filtration rate?
AIt is freely secreted by the tubule cells
BIt is reabsorbed in proportion to sodium
CIt is neither reabsorbed nor secreted
DIt is bound to albumin and never filtered
Answer & Solution
Correct answer: C. It is neither reabsorbed nor secreted
1. An ideal marker for filtration must leave the blood only by being filtered.
2. Inulin, a plant polysaccharide, is neither reabsorbed nor secreted by the kidney.
3. So the amount appearing in urine is directly proportional to the rate at which it was filtered.
4. A substance that was also secreted would overstate the filtration rate, and one that was reabsorbed would understate it.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 25 "The Urinary System", section 25.5 Physiology of Urine Formation_
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