Which paracrine signals do macula densa cells release?

1. Macula densa cells sense both the sodium concentration and the flow rate of the fluid passing them. 2. They report what they sense by releasing adenosine triphosphate and adenosine. 3. Those signals act locally on the juxtaglomerular cells of the afferent arteriole. 4. Renin is released by those juxtaglomerular cells rather than by the macula densa itself. 5. Aldosterone and ADH are endocrine hormones arriving from a distance, not local paracrine signals. _Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 25 "The Urinary System", section 25.4 Microscopic Anatomy of the Kidney_