alleryStart learning →Which enzyme deficiency is described as the most common one in humans?
AA shortage of the enzyme G6PD
BA shortage of the enzyme penicillinase
CA shortage of the enzyme hydrolase
DA shortage of the enzyme ligase
Answer & Solution
Correct answer: A. A shortage of the enzyme G6PD
1. Enzymes are the catalysts of cellular metabolism, so a missing enzyme can stall a whole pathway.
2. G6PD deficiency is a genetic condition that leaves too little glucose-6-phosphate dehydrogenase.
3. It is the most common enzyme deficiency in humans.
4. G6PD is the rate-limiting enzyme for the pathway that supplies NADPH to cells.
5. Hydrolases and ligases are whole classes of enzymes rather than named deficiencies.
_Source: OpenStax Chemistry (CC BY 4.0), Ch 12 "Kinetics", section 12.7 Catalysis_
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