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Sickle cell anaemia is inherited as
Aan autosomal recessive trait
Ban autosomal dominant trait
Ca sex linked dominant trait
Da chromosomal aneuploidy
Answer & Solution
Correct answer: A. an autosomal recessive trait
1. Mendelian disorders are classified by which chromosome carries them and whether they are dominant.
2. Sickle cell anaemia is an autosome linked recessive trait.
3. Autosome linked means it is not carried on a sex chromosome.
4. Recessive means both copies must carry the defect for the disease to appear.
5. A carrier with one copy is therefore unaffected, which matters for family counselling.
_Source: NCERT Class 12 Biology Ch4 'Principles of Inheritance and Variation'_
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