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Graft rejection after an organ transplant is due mainly to
Athe innate physical barriers
Bpassive immunity from the donor
Can antibody response to blood group antigens
Dthe cell mediated immune response
Answer & Solution
Correct answer: D. the cell mediated immune response
1. The body is able to differentiate self from nonself.
2. A graft from another individual carries nonself markers.
3. The cell mediated immune response is responsible for graft rejection.
4. This is why tissue matching and blood group matching are done before any transplant.
5. Even after matching, the patient takes immunosuppressants for life.
_Source: NCERT Class 12 Biology Ch7 'Human Health and Disease', section 7.2.2_
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