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A child has been diagnosed with cretinism. The most likely cause is:
A{'text': 'Excess insulin from pancreas'}
B{'text': 'Excess adrenaline from adrenal'}
C{'text': 'Deficiency of growth hormone only'}
D{'text': 'Deficiency of thyroxine since birth'}
Answer & Solution
Correct answer: D. {'text': 'Deficiency of thyroxine since birth'}
1. Cretinism is a condition of stunted physical and mental development from infancy.
2. It is caused by a **lack of thyroxine** in early life (often due to iodine deficiency).
3. Excess insulin causes hypoglycaemia, not cretinism; excess adrenaline gives anxiety symptoms.
4. Deficiency of growth hormone causes dwarfism — short stature without mental delay.
5. Hence cretinism is caused by thyroxine deficiency from birth.
_Source: Selina Concise ICSE Class 8 Biology Ch 5 "Endocrine System and Adolescence", Hormone-related disorders_
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