Home › Maharashtra HSC Class 12 (Science) › biology › Human Health and Diseases › Allergy is hypersensitivity reaction usually med…
Allergy is hypersensitivity reaction usually mediated by
AIgG antibodies only (typical)
Bphagocytes
CIgE antibodies and histamine release
Dcomplement only
Answer & Solution
Correct answer: C. IgE antibodies and histamine release
1. Allergens cross-link IgE bound to mast cells and basophils.
2. This triggers degranulation, releasing histamine and other mediators.
3. Histamine causes the classic symptoms of itching, swelling, increased mucus and bronchoconstriction.
_Source: Maharashtra Balbharati Std XII Biology, Ch 9 "Human Health and Diseases" §9.4_
Related questions