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Which enzyme binds at the origin of replication and separates the two strands of the DNA molecule during replication?
ADNA ligase
BDNA polymerase
CRNA primer
DHelicase
Answer & Solution
Correct answer: D. Helicase
1. Replication begins at the origin of replication where the strands open.
2. Helicase binds there and separates the two DNA strands.
3. DNA polymerase only adds nucleotides after the template is exposed, which rules out option B.
4. So the strand-separating enzyme is helicase, option D.
_Source: Samacheer Kalvi (TN SCERT) Class 10 Science, Unit 18 Genetics "DNA Replication", p.275_
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