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Klinefelter's syndrome is characterised by the karyotype:

A45, X0
B47, +21
C47, XYY
D47, XXY
Answer & Solution
Correct answer: D. 47, XXY
**Klinefelter's syndrome = 47, XXY** (extra X in a male). Overall masculine development but with gynaecomastia (breast development). Such individuals are sterile.
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