Sickle-cell anaemia is a:
AAutosome-linked recessive disorder
BX-linked recessive disorder
CY-linked disorder
DAutosomal dominant disorder
Answer & Solution
Correct answer: A. Autosome-linked recessive disorder
**Sickle-cell anaemia = autosome-linked recessive** trait. Diseased only in homozygotes Hb^S Hb^S. Heterozygotes Hb^A Hb^S show 'sickle-cell trait' (carrier, no full disease) and have some protection against malaria.
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