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HomeUP Board Class 12chemistryAlcohols, Phenols and Ethers › The Williamson ether synthesis works best with:

The Williamson ether synthesis works best with:

AA primary alkyl halide and a sodium alkoxide as nucleophile
BA tertiary alkyl halide and a sodium alkoxide for SN2 reaction
CA secondary alkyl halide and water as the only nucleophile
DA primary alkyl halide and aqueous KOH at high pressure
Answer & Solution
Correct answer: A. A primary alkyl halide and a sodium alkoxide as nucleophile
SN2 mechanism: primary R-X is least hindered; with alkoxide nucleophile it gives the ether cleanly.
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