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Phenylketonuria is cited in NCERT as an example of pleiotropy because:
AMultiple genes contribute additively to one trait
BOne gene affects multiple phenotypic traits
CThe disease shows incomplete dominance
DIt is determined by three alleles
Answer & Solution
Correct answer: A. Multiple genes contribute additively to one trait
Pleiotropy refers to a single gene producing multiple effects. The mutation in the phenylalanine hydroxylase gene leads to mental retardation along with reduced hair and skin pigmentation.
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