alleryThalassemia is classically autosomal recessive and primarily causes:
AExcess synthesis of every globin chain
BReplacement of all haemoglobin by myoglobin
CLoss of chromosome 21
DReduced synthesis of a globin chain
Answer & Solution
Correct answer: D. Reduced synthesis of a globin chain
Thalassemia is a quantitative defect: synthesis of an α- or β-globin chain is reduced. This differs from sickle-cell anaemia, where an altered globin chain is made.
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