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Heat unfolds an enzyme without cleaving its peptide chain. Which structural level is directly lost?

ATertiary structure
BPrimary structure
CNucleotide sequence
DAmino-acid identities
Answer & Solution
Correct answer: A. Tertiary structure
Tertiary structure is the overall three-dimensional folding of a polypeptide. Disrupting that fold can destroy the active site even if the amino-acid sequence remains intact.
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