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**Criss-cross inheritance** of an X-linked recessive trait (e.g. colour blindness) means the gene is transmitted from:
AFather to son directly
BFather to grandson **through** his (carrier) daughter
CMother to daughter directly with no carrier stage
DY chromosome of father to all sons
Answer & Solution
Correct answer: B. Father to grandson **through** his (carrier) daughter
Criss-cross pattern: affected father (X^c Y) passes X^c only to daughters (who become carriers X^c X). The carrier daughter passes X^c with 50% probability to her sons — who, lacking a second X to mask it, express the trait. So the disease 'skips' the daughter and re-emerges in the grandson — i.e. father → daughter (carrier) → grandson.
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